LmjF.30.2460

heat shock 70-related protein 1, mitochondrial precursor, putative
Leishmania major strain Friedlin OG6: OG6_100423 OG7: OG7_0000776 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.1370 ⚠
heat shock protein 110, putative
— +2 more OG7
LmjF.01.0640 ⚠
HSP70-like protein
— +2 more OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— +2 more OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— +2 more OG7
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— +8 more Both
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— Both
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— +8 more Both
LmjF.28.2820 ⚠
heat shock protein 70, putative
— +2 more OG6
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— +8 more Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— +8 more Both
LmjF.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmjF.30.0735 ⚠
heat shock protein grpe
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmjF.09.1130 ⚠
mitochondrial import inner membrane transloca
— Both
LmjF.25.0410 ⚠
translation initiation factor SUI1, putative
— Both
LmjF.26.0620 ⚠
10 kDa heat shock protein, putative
— Both
LmjF.35.3900 ⚠
hypothetical protein, conserved
— Both
LmjF.26.0640 ⚠
10 kDa heat shock protein, putative
— Both
LmjF.07.0220 ⚠
hypothetical protein, conserved
— Both
LmjF.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.30.2820 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LmjF.22.1030 ⚠
hypothetical protein, conserved
— Both
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.20.0210 ⚠
kelch domain-containing protein
— OG7
LmjF.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmjF.36.0120 ⚠
cap guanine-N7 methyltransferase
— OG7
LmjF.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LmjF.29.1400 ⚠
LYAR-type C2HC zinc finger, putative
— Both
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— Both
LmjF.27.1640 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— Both
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— Both
LmjF.24.0940 ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
LmjF.24.2240 ⚠
ATP:cob(I)alamin adenosyltransferase, putativ
— Both
LmjF.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
LmjF.13.0880 ⚠
hypothetical protein, conserved
— Both
LmjF.07.0720 ⚠
hypothetical protein, conserved
— Both
LmjF.22.0090 ⚠
cap guanylyltransferase-methyltransferase 1
— Both
LmjF.31.1750 ⚠
nucleosome assembly protein-like protein
— Both
LmjF.19.0440 ⚠
nucleosome assembly protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.