LmjF.01.0160

LSM domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_166948 OG7: OG7_0001217 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— +2 more OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.26.0005 ⚠
Lsm7p protein, putative
— +2 more OG7
LmjF.35.4460 ⚠
sm-f snRNP core complex protein, putative
— +2 more OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— +2 more OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— +2 more OG7
LmjF.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG7
LmjF.35.2770 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0735 ⚠
heat shock protein grpe
— OG7
LmjF.26.1280 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.33.0410 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.34.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.0920 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4920 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2760 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.26.1470 ⚠
farnesyltransferase beta subunit
— OG7
LmjF.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.35.3200 ⚠
RNA-binding protein, putative
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.26.1180 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4810 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.14.0910 ⚠
glutathione synthetase, putative
— OG7
LmjF.03.0450 ⚠
TLD domain protein, conserved
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.01.0380 ⚠
Dyggve-Melchior-Clausen syndrome protein, put
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.