LmjF.33.2260

glycosyl hydrolase-like protein
Leishmania major strain Friedlin OG6: OG6_104188 OG7: OG7_0008377 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmjF.28.0940
oxidoreductase-like protein
— Both
LmjF.30.0735 ⚠
heat shock protein grpe
— Both
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.20.1550 ⚠
amidohydrolase, putative
— Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.26.0010
brix domain containing-like protein
— Both
LmjF.20.0705
conserved protein, unknown function
— Both
LmjF.03.0970 ⚠
MORN repeat, putative
— OG7
LmjF.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— OG7
LmjF.29.0810
hypothetical protein, conserved
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.13.1350 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.13.0080 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.26.0390 ⚠
RET2, RNA editing complex MP57
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.28.0780 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LmjF.27.1870 ⚠
trypanothione synthetase
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.