LmjF.35.3250

replication factor C, subunit 3, putative
Leishmania major strain Friedlin OG6: OG6_100321 OG7: OG7_0001167 127 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 127 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.2320 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1470 ⚠
farnesyltransferase beta subunit
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.35.3360 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LmjF.35.3200 ⚠
RNA-binding protein, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.26.1180 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.35.4810 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LmjF.21.1130 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.29.2490 ⚠
protein kinase, putative
— OG7
LmjF.18.1320 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1050 ⚠
hypothetical protein, unknown function
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.12.0510 ⚠
WW domain containing protein, putative
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.11.0060 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmjF.34.2150 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LmjF.13.0620 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LmjF.09.1510 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.11.0930 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0650 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0320 ⚠
hypothetical protein, conserved
— OG7
LmjF.08.0110 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LmjF.23.0543 ⚠
5'-3' exoribonuclease C, putative
— OG7
LmjF.09.1100 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0450 ⚠
TLD domain protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.20.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.15.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.