LmjF.12.0510

WW domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_155789 OG7: OG7_0006042 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.29.0810 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.3060 ⚠
46 kD virulence factor
— OG7
LmjF.26.1120 ⚠
axonemal dynein light chain, putative
— OG7
LmjF.33.1780 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.33.1490 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2760 ⚠
gamma-tubulin complex component 3
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.35.1650 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.1640 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.30.1600 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.2700 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.14.0880 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0320 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.5020 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2480 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.11.0980 ⚠
HIT zinc finger, putative
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.31.0130 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.