LmjF.36.6430

protein transport protein Sec23-like protein
Leishmania major strain Friedlin OG6: OG6_100992 OG7: OG7_0004996 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.33.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0520 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.33.1880 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4150 ⚠
elongation factor 1-alpha, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.26.2320 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.12.0510 ⚠
WW domain containing protein, putative
— OG7
LmjF.11.0930 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.15.0520 ⚠
ecotin, putative
— OG7
LmjF.30.1850 ⚠
phosphatidylinositol kinase, putative
— OG7
LmjF.19.0750 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmjF.18.0990 ⚠
UDP-glucose pyrophosphorylase
— OG7
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.03.0690 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.21.0640 ⚠
phosphoglucomutase, putative
— OG7
LmjF.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LmjF.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.35.2840 ⚠
aminotransferase, putative
— OG7
LmjF.30.2090 ⚠
alcohol dehydrogenase, putative
— OG7
LmjF.25.1690 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.09.1100 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.