LmjF.03.0690

DEAD/DEAH box helicase, putative
Leishmania major strain Friedlin OG6: OG6_105684 OG7: OG7_0002665 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— Both
LmjF.27.0190 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LmjF.02.0310 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
LmjF.28.0110 ⚠
proteasome beta 3 subunit, putative
— Both
LmjF.11.0240 ⚠
proteasome alpha 7 subunit, putative
— +1 more Both
LmjF.07.0090 ⚠
methionine synthase, putative
— OG7
LmjF.03.0170 ⚠
hypothetical protein
— OG7
LmjF.07.0720 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.0500 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.05.1010 ⚠
methyltransferase-like protein
— OG7
LmjF.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmjF.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmjF.13.1660 ⚠
chaperonin TCP20, putative
— OG7
LmjF.35.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmjF.35.2300 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LmjF.21.1830 ⚠
proteasome subunit alpha type-5, putative
— OG7
LmjF.36.1600 ⚠
proteasome subunit alpha type-1, putative
— OG7
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmjF.36.1650 ⚠
proteasome subunit beta type-5, putative
— OG7
LmjF.35.2730 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LmjF.33.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.33.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.34.2810 ⚠
Carboxypeptidase-like protein
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.31.0360 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.