LmjF.33.2570

metallo-peptidase, Clan MF, Family M17
Leishmania major strain Friedlin OG6: OG6_105603 OG7: OG7_0003405 282 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 282 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.20.1570 ⚠
amidohydrolase, putative
— +7 more Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— +7 more Both
LmjF.31.1130 ⚠
amidohydrolase, putative
— +4 more OG7
LmjF.30.1380 ⚠
amidohydrolase, putative
— +7 more Both
LmjF.20.1550 ⚠
amidohydrolase, putative
— +7 more Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— OG7
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LmjF.36.4040 ⚠
hypothetical protein, conserved
— +2 more Both
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.30.0760 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— +1 more Both
LmjF.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— +1 more Both
LmjF.28.0330 ⚠
rrp44p homologue, putative
— +1 more Both
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.24.1880 ⚠
cyclin 11, putative
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
LmjF.29.1700 ⚠
MORN repeat, putative
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.32.0820 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.33.2740 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmjF.30.3630 ⚠
CYC2-like protein, putative
— OG7
LmjF.22.0060 ⚠
transcription factor-like protein
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.2770 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0880 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.31.2170 ⚠
ARM-like helical domain-containing protein
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.31.1480 ⚠
hypothetical protein, unknown function
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.28.1910 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.34.2360 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.