LmjF.33.2570

metallo-peptidase, Clan MF, Family M17

Leishmania major strain Friedlin OG6: OG6_105603 OG7: OG7_0003405 282 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 282 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.20.1570 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LmjF.20.1560 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LmjF.31.1130 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG7 LdBPK_110630.1 ↔ LdBPK_201720.1 OG7 LdBPK_110640.1 ↔ LdBPK_201720.1 OG7 LdBPK_110630.1 ↔ LdBPK_201740.1 +4 more	OG7
LmjF.30.1380 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LmjF.20.1550 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LmjF.34.2340 ⚠ asparaginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LmjF.30.0560 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	OG7
LmjF.07.0800 ⚠ flavoprotein subunit-like protein	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LmjF.35.0830 ⚠ NADH-dependent fumarate reductase-like protei	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LmjF.36.4040 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_332700.1 ↔ LdBPK_364240.1 OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 LdBPK_110630.1 ↔ LdBPK_364240.1 +2 more	Both
LmjF.08.0410 ⚠ WD domain, G-beta repeat, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	OG7
LmjF.30.0760 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG7 LdBPK_110630.1 ↔ LdBPK_300810.1	OG7
LmjF.35.1190 ⚠ NADH-dependent fumarate reductase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LmjF.35.1180 ⚠ NADH-dependent fumarate reductase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LmjF.01.0610 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 LdBPK_010630.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG7 LdBPK_010630.1 ↔ LdBPK_110630.1 OG7 LdBPK_010630.1 ↔ LdBPK_332700.1 +1 more	Both
LmjF.36.5620 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LmjF.30.0460 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	Both
LmjF.21.0895 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	Both
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 +1 more	Both
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 +1 more	Both
LmjF.17.0086 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.24.1880 ⚠ cyclin 11, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LmjF.23.0120 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG7 LdBPK_110630.1 ↔ LdBPK_332920.1	OG7
LmjF.25.0870 ⚠ Atypical serine/threonine protein kinase BUD3	—	OG7 LdBPK_110630.1 ↔ LdBPK_331490.1 OG7 LdBPK_110640.1 ↔ LdBPK_331490.1 OG7 LdBPK_331490.1 ↔ LdBPK_332700.1	OG7
LmjF.29.1700 ⚠ MORN repeat, putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_291830.1	OG7
LmjF.33.0770 ⚠ G1 cyclin CycE4, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LmjF.32.0820 ⚠ CYC2-like cyclin, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LmjF.33.2740 ⚠ translation initiation factor IF-2, putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_332880.1	OG7
LmjF.29.0600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_110640.1 ↔ LdBPK_220007.1 OG7 LdBPK_110630.1 ↔ LdBPK_290620.1	OG7
LmjF.36.0230 ⚠ peptidyl-prolyl cis-trans isomerase, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_291330.1 OG7 LdBPK_110640.1 ↔ LdBPK_291330.1 OG7 LdBPK_291330.1 ↔ LdBPK_332700.1	OG7
LmjF.18.0650 ⚠ PA26 p53-induced protein (sestrin), putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_180660.1	OG7
LmjF.30.3630 ⚠ CYC2-like protein, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LmjF.22.0060 ⚠ transcription factor-like protein	—	OG7 LdBPK_110640.1 ↔ LdBPK_220007.1 OG7 LdBPK_110630.1 ↔ LdBPK_290620.1	OG7
LmjF.15.1300 ⚠ ubiquitin hydrolase, putative	—	OG7 LdBPK_332700.1 ↔ LdBPK_343890.1	OG7
LmjF.35.2770 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_110640.1 ↔ LdBPK_352820.1	OG7
LmjF.22.0880 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_110630.1 ↔ LdBPK_220710.1	OG7
LmjF.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_290060.1 OG7 LdBPK_110640.1 ↔ LdBPK_290060.1 OG7 LdBPK_290060.1 ↔ LdBPK_332700.1	OG7
LmjF.31.2170 ⚠ ARM-like helical domain-containing protein	—	OG7 LdBPK_110640.1 ↔ LdBPK_312230.1	OG7
LmjF.36.2600 ⚠ cyclin-e binding protein 1-like protein	—	OG7 LdBPK_110630.1 ↔ LdBPK_260720.1 OG7 LdBPK_110640.1 ↔ LdBPK_260720.1 OG7 LdBPK_260720.1 ↔ LdBPK_332700.1	OG7
LmjF.18.0600 ⚠ Zn-finger in Ran binding protein and others/F	—	OG7 LdBPK_110640.1 ↔ LdBPK_180610.1	OG7
LmjF.31.1480 ⚠ hypothetical protein, unknown function	—	OG7 LdBPK_110640.1 ↔ LdBPK_311510.1	OG7
LmjF.04.0250 ⚠ RNA pseudouridylate synthase-like protein	—	OG7 LdBPK_110630.1 ↔ LdBPK_261140.1 OG7 LdBPK_110640.1 ↔ LdBPK_261140.1 OG7 LdBPK_261140.1 ↔ LdBPK_332700.1	OG7
LmjF.28.1910 ⚠ p21-C-terminal region-binding protein, putati	—	OG7 LdBPK_110640.1 ↔ LdBPK_282030.1	OG7
LmjF.10.0890 ⚠ FKBP-type peptidyl-prolyl cis-trans isomerase	—	OG7 LdBPK_110630.1 ↔ LdBPK_291330.1 OG7 LdBPK_110640.1 ↔ LdBPK_291330.1 OG7 LdBPK_291330.1 ↔ LdBPK_332700.1	OG7
LmjF.34.2360 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003865	OG7
LmjF.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_001709	OG7
LmjF.05.0180 ⚠ dihydrolipoamide branched chain transacylase,	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_009880	OG7
LmjF.32.2910 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005374	OG7
LmjF.24.0820 ⚠ inositol polyphosphate phosphatase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007569	OG7

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