LmjF.22.0880

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_158212 OG7: OG7_0043919 32 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 32 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.22.0060 ⚠
transcription factor-like protein
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.19.0220
polyprenyl synthase, putative
— Both
LmjF.26.2350
hypothetical protein, conserved
— Both
LmjF.36.2080
streptococcal hemagglutinin-like protein
— Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.29.0600 ⚠
hypothetical protein, conserved
— Both
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.30.0760
hypothetical protein, conserved
— Both
LmjF.35.2270
ATP-dependent RNA helicase-like protein
— OG6
LmjF.29.1250
hypothetical protein, unknown function
— Both
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— Both
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— Both
LmjF.36.5620
isoleucyl-tRNA synthetase, putative
— Both
LmjF.18.0650
PA26 p53-induced protein (sestrin), putative
— Both
LmjF.17.1030
hypothetical protein, conserved
— Both
LmjF.17.1410
zinc-finger protein ZPR1, putative
— Both
LmjF.07.0720 ⚠
hypothetical protein, conserved
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.