LmjF.35.2270

ATP-dependent RNA helicase-like protein
Leishmania major strain Friedlin OG6: OG6_146576 OG7: OG7_0000698 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.22.1580 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG6
LmjF.26.0470
hypothetical protein, conserved
— OG6
LmjF.03.0170
hypothetical protein
— OG6
LmjF.01.0610
DNA-damage inducible protein DDI1-like protei
— OG6
LmjF.14.0410
Protein of unknown function (DUF1253), putati
— OG6
LmjF.17.0940
Phosphorylated CTD interacting factor 1 WW do
— OG6
LmjF.29.2150
cdc2-related kinase 10, putative
— OG6
LmjF.30.0470
hypothetical protein, conserved
— OG6
LmjF.13.0640
hypothetical protein, conserved
— OG6
LmjF.14.1360
inositol-3-phosphate synthase
— OG6
LmjF.14.1140
hypothetical protein, conserved
— OG6
LmjF.03.0690
DEAD/DEAH box helicase, putative
— OG6
LmjF.35.4850
proteasome alpha 1 subunit, putative
— OG6
LmjF.28.0110
proteasome beta 3 subunit, putative
— OG6
LmjF.35.3840
proteasome beta 2 subunit, putative
— OG6
LmjF.11.0260
hypothetical protein, conserved
— OG6
LmjF.31.2970
acetyl-CoA carboxylase
— OG6
LmjF.21.1090
T-complex protein 1, delta subunit, putative
— OG6
LmjF.32.3460 ⚠
exosome-associated protein 2, putative
— OG6
LmjF.03.0130
acetyltransferase, putative
— OG6
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
LmjF.12.0030
proteasome beta-1 subunit, putative
— OG6
LmjF.08.1130
phosphoribosylpyrophosphate synthetase
— OG6
LmjF.21.1700
proteasome alpha 2 subunit, putative
— OG6
LmjF.11.0240
proteasome alpha 7 subunit, putative
— OG6
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
LmjF.29.1460
hypothetical protein, conserved
— OG6
LmjF.34.3080
exosome subunit rrp6p homologue, putative
— OG6
LmjF.27.1970
small nuclear ribonucleoprotein protein, puta
— OG6
LmjF.15.0090
ATP-dependent protease ATPase subunit HslU1,
— OG6
LmjF.12.0280
ornithine decarboxylase, putative
— OG6
LmjF.25.0410
translation initiation factor SUI1, putative
— OG6
LmjF.28.0330
rrp44p homologue, putative
— OG6
LmjF.29.0600
hypothetical protein, conserved
— OG6
LmjF.20.1570 ⚠
amidohydrolase, putative
— OG6
LmjF.20.1560 ⚠
amidohydrolase, putative
— OG6
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG6
LmjF.30.1380 ⚠
amidohydrolase, putative
— OG6
LmjF.19.0220
polyprenyl synthase, putative
— OG6
LmjF.25.0800
DNL zinc finger, putative
— OG6
LmjF.25.1080
hypothetical protein, conserved
— OG6
LmjF.22.0880
hypothetical protein, conserved
— OG6
LmjF.16.0310
Met-10+ like-protein, putative
— OG6
LmjF.32.3270
chaperonin alpha subunit, putative
— OG6
LmjF.34.0350
eukaryotic translation initiation factor 5, p
— OG6
LmjF.18.0650
PA26 p53-induced protein (sestrin), putative
— OG6
LmjF.25.1030
hypothetical protein, conserved
— OG6
LmjF.11.1170
eukaryotic release factor 3, putative
— OG6
LmjF.35.1200 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LmjF.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.