LmjF.27.2050

ribonucleoside-diphosphate reductase small chain, putative
Leishmania major strain Friedlin OG6: OG6_100537 OG7: OG7_0003661 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— Both
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.20.0705 ⚠
conserved protein, unknown function
— Both
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
LmjF.20.1550 ⚠
amidohydrolase, putative
— Both
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
LmjF.35.4550 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2980 ⚠
hypothetical protein, conserved
— Both
LmjF.36.4040 ⚠
hypothetical protein, conserved
— Both
LmjF.25.1080 ⚠
hypothetical protein, conserved
— OG6
LmjF.25.1680 ⚠
hypothetical protein, unknown function
— Both
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LmjF.33.2830 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LmjF.33.2850 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.34.1470 ⚠
EAP30/Vps36 family, putative
— Both
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.29.0340 ⚠
UBX domain-containing protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.