LmjF.17.0085

elongation factor 1-alpha
Leishmania major strain Friedlin OG6: OG6_100227 OG7: OG7_0001444 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.36.4040 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.15.0690 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.0880 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.29.2210 ⚠
leucine-rich repeat-containing protein
— OG7
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.36.5590 ⚠
adenylyl cyclase-associated protein, putative
— OG7
LmjF.27.1970 ⚠
small nuclear ribonucleoprotein protein, puta
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LmjF.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LmjF.14.0410 ⚠
Protein of unknown function (DUF1253), putati
— OG7
LmjF.29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.03.0170 ⚠
hypothetical protein
— OG7
LmjF.26.1290 ⚠
Cupin-like domain containing protein, putativ
— OG7
LmjF.16.1425 ⚠
Paraflagellar rod protein 2-3
— OG7
LmjF.16.1427 ⚠
Paraflagellar rod protein 2-2
— OG7
LmjF.16.1430 ⚠
Paraflagellar rod protein 2-1
— OG7
LmjF.11.1000 ⚠
pyruvate phosphate dikinase, putative
— OG7
LmjF.33.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmjF.09.0940 ⚠
translation-associated element 2, putative
— OG7
LmjF.28.1530 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LmjF.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LmjF.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmjF.30.1400 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.15.1420 ⚠
mismatch repair protein MSH3, putative
— OG7
LmjF.02.0310 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LmjF.33.1910 ⚠
ribosome assembly protein RRB1, putative
— OG7
LmjF.36.1950 ⚠
DNA mismatch repair protein MSH6, putative
— OG7
LmjF.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.