LmjF.36.5590

adenylyl cyclase-associated protein, putative
Leishmania major strain Friedlin OG6: OG6_101374 OG7: OG7_0005390 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.15.1220 ⚠
DnaJ domain/DnaJ central domain containing pr
— OG7
LmjF.25.1100 ⚠
DNAj-like protein
— OG7
LmjF.35.2980 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.04.0780 ⚠
heat shock protein, putative
— OG7
LmjF.36.2110 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.22.0080 ⚠
heat shock protein DNAJ, putative
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.33.0900 ⚠
dnaj chaperone-like protein
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.35.4150 ⚠
elongation factor 1-alpha, putative
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.25.0410
translation initiation factor SUI1, putative
— Both
LmjF.28.2370 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LmjF.14.1320 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LmjF.33.2390
heat shock protein, putative
— OG6
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.32.3300 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.15.0970
E1-like ubiquitin-activating enzyme, putative
— Both
LmjF.29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LmjF.36.4040
hypothetical protein, conserved
— Both
LmjF.13.0880
hypothetical protein, conserved
— Both
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— Both
LmjF.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.