LmjF.15.1300

ubiquitin hydrolase, putative
Leishmania major strain Friedlin OG6: OG6_145141 OG7: OG7_0002166 235 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 235 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— Both
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.04.0030 ⚠
cAMP-specific phosphodiesterase, putative
— Both
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.35.0750 ⚠
proteasome activator protein pa26, putative
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.24.0990 ⚠
replication factor C, subunit 1, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.33.2960 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.30.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.13.0880 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.30.3130 ⚠
valyl-tRNA synthetase, putative
— OG7
LmjF.31.2130 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.0410 ⚠
translation initiation factor SUI1, putative
— OG7
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.08.0320 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.30.3080 ⚠
homoserine kinase
— OG7
LmjF.15.0690 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.