LmjF.05.0460

GTPase, putative
Leishmania major strain Friedlin OG6: OG6_101829 OG7: OG7_0001608 235 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 235 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.30.3410 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.0860 ⚠
60S ribosomal protein L13a, putative
— OG7
LmjF.15.0200 ⚠
60S ribosomal protein L13a, putative
— OG7
LmjF.32.3130 ⚠
ribosomal protein L3, putative
— OG7
LmjF.34.2890 ⚠
ribosomal protein L3, putative
— OG7
LmjF.34.2870 ⚠
ribosomal protein L3, putative
— OG7
LmjF.34.2900 ⚠
ribosomal protein L3, putative
— OG7
LmjF.34.2880 ⚠
ribosomal protein L3, putative
— OG7
LmjF.06.0570 ⚠
60S ribosomal protein L23a, putative
— OG7
LmjF.06.0580 ⚠
60S ribosomal protein L23a, putative
— OG7
LmjF.13.0140 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.5840 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2910 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.04.0750 ⚠
60S ribosomal protein L10, putative
— OG7
LmjF.04.0950 ⚠
60S ribosomal protein L10, putative
— OG7
LmjF.35.1910 ⚠
ribosomal protein L15, putative
— OG7
LmjF.30.3650 ⚠
ribosomal protein L15, putative
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.17.1310 ⚠
methyltransferase domain containing protein,
— OG7
LmjF.27.1680 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.34.2750 ⚠
methyltransferase-like protein
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.35.3260 ⚠
Peroxin 19
— OG7
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.6220 ⚠
flagellum transition zone component, putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
LmjF.30.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.26.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1480 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmjF.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— OG7
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.11.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0020 ⚠
histone H4
— OG7
LmjF.15.0010 ⚠
histone H4
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.27.0940 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.