LmjF.35.0750

proteasome activator protein pa26, putative
Leishmania major strain Friedlin OG6: OG6_132802 OG7: OG7_0037801 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.0820 ⚠
SET domain containing protein, putative
— OG7
LmjF.36.5590
adenylyl cyclase-associated protein, putative
— Both
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmjF.25.0410
translation initiation factor SUI1, putative
— Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.29.1780 ⚠
diphthamide synthesis protein, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.24.1750 ⚠
SET domain containing protein, putative
— OG7
LmjF.23.0790 ⚠
SET domain containing protein, putative
— OG7
LmjF.34.1050 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LmjF.27.0160 ⚠
SET domain containing protein, putative
— OG7
LmjF.36.4780
paraflagellar rod component, putative
— Both
LmjF.08.0880 ⚠
SET domain containing protein, putative
— OG7
LmjF.33.0510 ⚠
SET domain containing protein, putative
— OG7
LmjF.06.1000 ⚠
SET domain containing protein, putative
— OG7
LmjF.12.1300 ⚠
SET domain containing protein, putative
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.13.0730 ⚠
ubiquitin-like protein
— Both
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.04.0990
hypothetical protein, conserved
— Both
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— Both
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.13.0880
hypothetical protein, conserved
— Both
LmjF.07.0870
splicing factor ptsr1-like protein
— Both
LmjF.05.0740
Vta1 like, putative
— Both
LmjF.05.0390 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
LmjF.30.0600 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
LmjF.30.3050 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
LmjF.15.0690
hypothetical protein, conserved
— Both
LmjF.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LmjF.14.0910
glutathione synthetase, putative
— Both
LmjF.24.0140
ankyrin/TPR repeat protein
— OG6
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.29.1470
hypothetical protein, conserved
— Both
LmjF.33.2410 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— Both
LmjF.14.1360
inositol-3-phosphate synthase
— Both
LmjF.23.1010
hypothetical protein, conserved
— Both
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.