LmjF.26.0900

heat shock 70 protein-like protein
Leishmania major strain Friedlin OG6: OG6_139806 OG7: OG7_0000779 183 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 183 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.2460 ⚠
heat shock 70-related protein 1, mitochondria
— +2 more OG7
LmjF.30.2470 ⚠
heat shock 70-related protein 1, mitochondria
— +2 more OG7
LmjF.30.2550 ⚠
heat shock 70-related protein 1, mitochondria
— +2 more OG7
LmjF.30.2490 ⚠
heat shock 70-related protein 1, mitochondria
— +2 more OG7
LmjF.30.2480 ⚠
heat shock 70-related protein 1, mitochondria
— +2 more OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— +2 more OG7
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— +2 more OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— +2 more OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— +2 more OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— +2 more OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— +2 more OG7
LmjF.01.0640 ⚠
HSP70-like protein
— +2 more OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.35.2350 ⚠
aminopeptidase P, putative
— OG7
LmjF.36.5560 ⚠
aminopeptidase P1, putative
— OG7
LmjF.01.0530 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.03.0230 ⚠
long chain fatty Acyl CoA synthetase, putativ
— OG7
LmjF.01.0470 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LmjF.01.0520 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— OG7
LmjF.01.0490 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.03.0600 ⚠
arginine N-methyltransferase, putative
— OG7
LmjF.28.2910 ⚠
glutamate dehydrogenase, putative
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.25.1700 ⚠
Leucine-rich repeat, putative
— OG7
LmjF.09.0840 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
LmjF.29.0867 ⚠
guanine deaminase, putative
— OG7
LmjF.32.0170 ⚠
U2 small nuclear ribonucleoprotein 40K, putat
— OG7
LmjF.07.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3310 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.11.1170 ⚠
eukaryotic release factor 3, putative
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.25.1390 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LmjF.26.0480 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LmjF.06.0870 ⚠
protein arginine n-methyltransferase 7
— OG7
LmjF.36.0710 ⚠
Protein C21orf2 homolog, putative
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.03.0120 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0830 ⚠
aspartate--ammonia ligase, putative
— OG7
LmjF.36.3590 ⚠
cysteine synthase
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmjF.12.1270 ⚠
arginine N-methyltransferase-like protein
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.16.0030 ⚠
arginine N-methyltransferase, type I
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.