LmjF.26.1220

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_146995 OG7: OG7_0007518 126 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 126 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.2220 ⚠
Solute carrier (proton/amino acid symporter),
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.01.0060 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0660 ⚠
Nop14-like family, putative
— OG7
LmjF.18.0850 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.30.0060 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2850 ⚠
ribosomal protein l7/l12-like protein
— OG7
LmjF.14.0150 ⚠
60S ribosomal protein, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.03.0630 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.32.2670 ⚠
kinteoplast poly(A) polymerase complex 1 subu
— OG7
LmjF.32.1770 ⚠
phosphatidylethanolamine-binding protein, put
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.25.0420 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0780 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0470 ⚠
pumillio protein 10, putative
— OG7
LmjF.28.2810 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0100 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LmjF.33.2630 ⚠
dynein intermediate chain, putative
— OG7
LmjF.14.1130 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.05.0140 ⚠
nucleolar RNA helicase II, putative
— OG7
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.