LmjF.15.0300

Ecotin-like protein
Leishmania major strain Friedlin OG6: OG6_173648 OG7: OG7_0025883 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.1880 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.21.1552 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LmjF.32.0985 ⚠
Vps23 core domain containing protein, putativ
— OG7
LmjF.30.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1600 ⚠
ser/thr protein phosphatase, putative
— OG7
LmjF.28.1530 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmjF.26.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.19.0160 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LmjF.01.0780 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.15.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.29.2360 ⚠
aspartyl aminopeptidase, putative
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG7
LmjF.11.0930 ⚠
hypothetical protein, conserved
— OG7
LmjF.09.1100 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0450 ⚠
TLD domain protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.11.0920 ⚠
Short C-terminal domain/PUB domain containing
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.13.0680 ⚠
Metallopeptidase family M24, putative
— OG7
LmjF.32.0730 ⚠
Outer row dynein-assembly protein 7
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.33.2520 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— OG7
LmjF.35.0370 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LmjF.35.4810 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.01.0770 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LmjF.22.0530 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.26.2320 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG7
LmjF.34.0140 ⚠
malate dehydrogenase
— OG7
LmjF.23.0543 ⚠
5'-3' exoribonuclease C, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LmjF.03.0690 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.07.0940 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.