LmjF.32.0985

Vps23 core domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_137361 OG7: OG7_0005919 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.21.1040
kinesin, putative
— Both
LmjF.15.0510 ⚠
ecotin, putative
— OG7
LmjF.15.0300 ⚠
Ecotin-like protein
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.25.1820
hypothetical protein, conserved
— Both
LmjF.18.1020
hypothetical protein, unknown function
— Both
LmjF.07.0310
paraflagellar rod protein, putative
— Both
LmjF.19.1160
hypothetical protein, conserved
— Both
LmjF.27.2480
WD-repeat protein
— Both
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
LmjF.35.5260
hypothetical protein, conserved
— Both
LmjF.32.2840
prefoldin subunit, putative
— Both
LmjF.35.0090
hypothetical protein, conserved
— Both
LmjF.35.2380
hypothetical protein, unknown function
— Both
LmjF.30.1450
kinesin, putative
— Both
LmjF.21.0330
Vps51/Vps67, putative
— Both
LmjF.15.0520 ⚠
ecotin, putative
— Both
LmjF.25.1570
ER-golgi trafficking TRAPP I complex 85 kDa s
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.