LmjF.27.2480

WD-repeat protein
Leishmania major strain Friedlin OG6: OG6_102145 OG7: OG7_0007160 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.4820
WD domain, G-beta repeat, putative
— Both
LmjF.15.0790
hypothetical protein, unknown function
— Both
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.34.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmjF.34.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmjF.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmjF.09.1220
AAA family ATPase, putative
— Both
LmjF.27.0880 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
LmjF.36.3470 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
LmjF.06.1160
hypothetical protein, conserved
— Both
LmjF.12.0610 ⚠
TPR repeat, putative
— Both
LmjF.21.0320
U1 small nuclear ribonucleoprotein C, putativ
— Both
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.25.1820
hypothetical protein, conserved
— Both
LmjF.18.1020
hypothetical protein, unknown function
— Both
LmjF.19.0680 ⚠
Flagellum attachment zone protein 7
— OG6
LmjF.19.0690 ⚠
Flagellum attachment zone protein 7
— OG6
LmjF.04.0690
axonemal dynein light chain, putative
— Both
LmjF.22.1630
ccr4-not transcription complex subunit
— Both
LmjF.27.1970
small nuclear ribonucleoprotein protein, puta
— Both
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LmjF.07.0310
paraflagellar rod protein, putative
— Both
LmjF.19.1160
hypothetical protein, conserved
— Both
LmjF.21.1040
kinesin, putative
— Both
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.32.0715 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmjF.36.0535 ⚠
U2 small nuclear ribonucleoprotein 16.5K, put
— OG7
LmjF.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.18.0790 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LmjF.35.1020 ⚠
hypothetical protein, unknown function
— OG7
LmjF.15.0140 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.15.0160 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.27.0130 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LmjF.35.1040 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.05.0410 ⚠
TPR repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.