LmjF.12.0610

TPR repeat, putative
Leishmania major strain Friedlin OG6: OG6_102790 OG7: OG7_0003813 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.05.0410 ⚠
TPR repeat, putative
— Both
LmjF.04.0400 ⚠
anaphase promoting complex, subunit 10-like p
— +2 more Both
LmjF.06.1160 ⚠
hypothetical protein, conserved
— +1 more Both
LmjF.24.0930 ⚠
hypothetical protein, conserved
— +2 more Both
LmjF.30.0710 ⚠
CDC16, putative
— +2 more Both
LmjF.30.1990 ⚠
cyclosome subunit-like protein
— +2 more Both
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.2210 ⚠
endosomal trafficking protein RME-8, putative
— Both
LmjF.35.4010 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
LmjF.29.2250 ⚠
hypothetical protein, conserved
— Both
LmjF.24.1970 ⚠
Nucleoporin NUP76
— Both
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LmjF.16.0780 ⚠
N-terminal region of Chorein, a TM vesicle-me
— Both
LmjF.09.1220 ⚠
AAA family ATPase, putative
— Both
LmjF.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmjF.34.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmjF.34.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.34.1390 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.21.0023 ⚠
ring-box protein 1, putative
— OG7
LmjF.24.1610 ⚠
ring-box protein, putative
— OG7
LmjF.16.0650 ⚠
RING-H2 zinc finger, putative
— OG7
LmjF.32.3150 ⚠
Flagellar Member 7
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.