LmjF.34.2520

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain/Domain of unknown function (DUF1981), putative
Leishmania major strain Friedlin OG6: OG6_154458 OG7: OG7_0001170 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.04.0530 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.26.1950 ⚠
microtubule-associated protein, putative
— OG7
LmjF.28.2390 ⚠
WW domain containing protein, putative
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.20.0260 ⚠
Midasin, putative
— OG7
LmjF.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmjF.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmjF.18.0460 ⚠
tubulin-specific chaperone, putative
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.13.0270 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0510 ⚠
WW domain containing protein, putative
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.35.2380 ⚠
hypothetical protein, unknown function
— OG7
LmjF.32.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmjF.34.4310 ⚠
coatomer alpha subunit, putative
— OG7
LmjF.36.4820 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.31.0130 ⚠
hypothetical protein, unknown function
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.15.0790 ⚠
hypothetical protein, unknown function
— OG7
LmjF.17.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.34.0840 ⚠
translation elongation factor 1-beta, putativ
— OG7
LmjF.36.6980 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.27.2480 ⚠
WD-repeat protein
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.0820 ⚠
elongation factor 1-beta
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.33.0280 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6340 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.19.0100 ⚠
fibrillarin, putative
— OG7
LmjF.05.0410 ⚠
TPR repeat, putative
— OG7
LmjF.10.0950 ⚠
translation initiation factor eIF-2B subunit
— OG7
LmjF.15.0700 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1580 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.0740 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LmjF.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmjF.35.4330 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmjF.18.1240 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmjF.33.2250 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0100 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1060 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.