LmjF.18.0460

tubulin-specific chaperone, putative
Leishmania major strain Friedlin OG6: OG6_102852 OG7: OG7_0002326 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.3070 ⚠
fibrillarin
— OG7
LmjF.33.1490 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.23.0900 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.21.0530 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.30.0490 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1840 ⚠
General negative regulator of transcription s
— OG7
LmjF.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.34.1510 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0800 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
LmjF.32.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.26.1950 ⚠
microtubule-associated protein, putative
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.20.0260 ⚠
Midasin, putative
— OG7
LmjF.24.1960 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.32.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmjF.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.33.0280 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6340 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.06.0340 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.34.4400 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4430 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4340 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4460 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4490 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4370 ⚠
20s proteasome beta 7 subunit, (putative)
— OG7
LmjF.34.4520 ⚠
proteasome beta 7 subunit, putative
— OG7
LmjF.09.0770 ⚠
oligopeptidase b
— OG7
LmjF.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0100 ⚠
fibrillarin, putative
— OG7
LmjF.27.0500 ⚠
calpain-like cysteine peptidase, putative
— OG7
LmjF.27.0510 ⚠
calpain-like cysteine peptidase, putative
— OG7
LmjF.27.0490 ⚠
calpain-like cysteine peptidase, putative
— OG7
LmjF.11.0830 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmjF.04.0550 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.