LmjF.30.0490

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_196761 OG7: OG7_0043598 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— Both
LmjF.30.0050
MATH domain containing protein, putative
— Both
LmjF.24.1960
hypothetical protein, conserved
— Both
LmjF.29.2250
hypothetical protein, conserved
— Both
LmjF.29.0970
kinesin, putative
— OG6
LmjF.25.0610 ⚠
Regulatory-associated protein of TOR1
— Both
LmjF.14.0930
tc40 antigen-like
— Both
LmjF.26.1950 ⚠
microtubule-associated protein, putative
— Both
LmjF.12.0610 ⚠
TPR repeat, putative
— Both
LmjF.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmjF.24.0930
hypothetical protein, conserved
— Both
LmjF.22.0570
proteasome regulatory ATPase subunit 1, putat
— OG6
LmjF.12.0010 ⚠
translation initiation factor EIF-2b alpha su
— Both
LmjF.09.1220
AAA family ATPase, putative
— Both
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.1210 ⚠
translation initiation factor eIF2B delta sub
— OG7
LmjF.10.0950 ⚠
translation initiation factor eIF-2B subunit
— OG7
LmjF.34.1390 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.09.0990 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.33.3060 ⚠
46 kD virulence factor
— OG7
LmjF.34.2450 ⚠
Sec7 domain containing protein, putative
— OG7
LmjF.34.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.