LmjF.18.1100

Ankyrin repeats (3 copies), putative
Leishmania major strain Friedlin OG6: OG6_123075 OG7: OG7_0000441 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.11.0390 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LmjF.35.1250 ⚠
monothiol glutaredoxin, putative
— OG7
LmjF.01.0110 ⚠
monothiol glutaredoxin, putative
— OG7
LmjF.05.0310 ⚠
monothiol glutaredoxin, putative
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6465 ⚠
hypothetical protein, unknown function
— OG7
LmjF.17.0360 ⚠
cytidine deaminase-like protein
— OG7
LmjF.22.1280 ⚠
hypothetical protein, unknown function
— OG7
LmjF.29.1340 ⚠
RNA-binding protein, putative
— OG7
LmjF.20.1240 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LmjF.31.2570 ⚠
hypothetical protein, unknown function
— OG7
LmjF.18.0180 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LmjF.29.1350 ⚠
RNA binding protein, putative
— OG7
LmjF.18.0170 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LmjF.34.1155 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
LmjF.18.0190 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LmjF.26.2110 ⚠
protein kinase, putative
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.36.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.0520 ⚠
RNA-binding protein, putative
— OG7
LmjF.29.1370 ⚠
RNA binding protein, putative
— OG7
LmjF.35.3070 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1490 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.32.1790 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0390 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.13.0550 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LmjF.18.0220 ⚠
RNA-binding protein 29, putative
— OG7
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.18.1040 ⚠
5-oxoprolinase, putative
— OG7
LmjF.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LmjF.35.2300 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.34.1410 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmjF.04.1190 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LmjF.35.5310 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.36.2250 ⚠
developmentally regulated GTP-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.