LmjF.25.1730

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_158193 OG7: OG7_0052300 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.18.0220
RNA-binding protein 29, putative
— Both
LmjF.36.2250 ⚠
developmentally regulated GTP-binding protein
— Both
LmjF.34.0480
calcium channel protein, putative
— Both
LmjF.28.1170
AN1-like zinc finger, putative
— Both
LmjF.35.4280 ⚠
Spindle assembly abnormal protein 6 homolog
— Both
LmjF.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— Both
LmjF.22.1030 ⚠
hypothetical protein, conserved
— Both
LmjF.11.1370
tRNA pseudouridine synthase D (TruD), putativ
— Both
LmjF.25.0540
hypothetical protein SCD6.10
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.29.1100 ⚠
Ankyrin repeats (3 copies), putative
— Both
LmjF.33.0440
hypothetical protein, conserved
— Both
LmjF.35.3070
hypothetical protein, conserved
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmjF.35.5310 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.20.0210 ⚠
kelch domain-containing protein
— OG7
LmjF.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LmjF.32.2650 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.34.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.04.0090
hypothetical protein, conserved
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.27.0130 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LmjF.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmjF.19.0450
hypothetical protein, conserved
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.31.0255 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6640 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1040 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LmjF.15.0160 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.