LmjF.34.3550

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_136955 OG7: OG7_0004545 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.30.1980 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.27.0860 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.22.1130 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.22.1120 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0520 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.31.2020 ⚠
succinyl-diaminopimelate desuccinylase-like p
— OG7
LmjF.26.2090 ⚠
hypothetical protein, unknown function
— OG7
LmjF.28.1820 ⚠
Replication factor A protein 1
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.30.3440 ⚠
DNA ligase I, putative
— OG7
LmjF.11.0390 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.1240 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LmjF.26.0580 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.24.1490 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.18.1040 ⚠
5-oxoprolinase, putative
— OG7
LmjF.32.1790 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.0550 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.34.1400 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.29.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.1190 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LmjF.35.2300 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.1890 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LmjF.33.1610 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LmjF.33.3050 ⚠
tyrosyl-DNA phosphodiesterase 1
— OG7
LmjF.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.11.0700 ⚠
anion-transporting ATPase-like protein
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.33.2610 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.36.2250 ⚠
developmentally regulated GTP-binding protein
— OG7
LmjF.35.5310 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LmjF.18.0220 ⚠
RNA-binding protein 29, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.