LmjF.31.1930

dihydrouridine synthase (Dus), putative
Leishmania major strain Friedlin OG6: OG6_101867 OG7: OG7_0002064 214 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 214 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.1120 ⚠
importin alpha, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.36.6070 ⚠
disgorgin, putative
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.18.0090 ⚠
alpha glucosidase II subunit, putative
— OG7
LmjF.31.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.22.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0630 ⚠
histidyl-tRNA synthetase, putative
— OG7
LmjF.17.1450 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LmjF.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LmjF.30.2840 ⚠
GTPase activator-like protein
— OG7
LmjF.20.1150 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
LmjF.36.5620 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.2120 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LmjF.35.5060 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.2730 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LmjF.36.2840 ⚠
Flagellar Member 2
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.11.0530 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.18.0700 ⚠
HEAT repeats, putative
— OG7
LmjF.31.2600 ⚠
calreticulin, putative
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.