LmjF.36.5620

isoleucyl-tRNA synthetase, putative
Leishmania major strain Friedlin OG6: OG6_100811 OG7: OG7_0003029 197 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 197 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.13.1100
leucyl-tRNA synthetase, putative
— Both
LmjF.20.1550 ⚠
amidohydrolase, putative
— Both
LmjF.22.0470 ⚠
Putative tRNA binding domain containing prote
— +1 more Both
LmjF.16.1130 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— +1 more Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.14.1370 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.25.0410
translation initiation factor SUI1, putative
— Both
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.32.3980
Gar1/Naf1 RNA binding region, putative
— Both
LmjF.29.0600 ⚠
hypothetical protein, conserved
— Both
LmjF.30.0730 ⚠
co-chaperone GrpE, putative
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
LmjF.35.0900
hypothetical protein, conserved
— Both
LmjF.35.0350
hypothetical protein, conserved
— Both
LmjF.35.2730
acyl-CoA dehydrogenase, putative
— Both
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— Both
LmjF.25.2120
eukaryotic translation initiation factor 3 su
— Both
LmjF.35.0390
hypothetical protein, conserved
— Both
LmjF.28.2370 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LmjF.27.0380
Nuclear pore complex protein 158
— Both
LmjF.35.1420
peroxisome targeting signal 1 receptor, putat
— Both
LmjF.36.0130
PUB domain containing protein, putative
— Both
LmjF.14.0450 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LmjF.17.0980
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LmjF.27.1310
arginyl-tRNA synthetase, putative
— Both
LmjF.25.2410
hypothetical protein, conserved
— Both
LmjF.29.2540 ⚠
NOL1/NOP2/sun family, putative
— Both
LmjF.35.4550
hypothetical protein, conserved
— Both
LmjF.18.0880
cyclosporin 16, putative
— OG6
LmjF.33.1120
hypothetical protein, conserved
— Both
LmjF.36.4040
hypothetical protein, conserved
— Both
LmjF.18.0090 ⚠
alpha glucosidase II subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.