LmjF.36.5620

isoleucyl-tRNA synthetase, putative

Leishmania major strain Friedlin OG6: OG6_100811 OG7: OG7_0003029 197 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 197 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.30.1380 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LmjF.34.2340 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
LmjF.33.2570 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LmjF.13.1100 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LmjF.20.1550 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LmjF.22.0470 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LmjF.16.1130 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LmjF.11.0630 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LmjF.11.0620 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LmjF.20.1560 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LmjF.21.0895 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LmjF.14.1370 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 Tb927.10.9190 ↔ Tb927.8.5330	Both
LmjF.20.1570 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LmjF.30.0460 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LmjF.31.1130 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	OG7
LmjF.24.0480 ⚠ Kelch motif/Galactose oxidase, central domain	—	OG7 LdBPK_220850.1 ↔ LdBPK_365870.1	OG7
LmjF.16.0080 ⚠ Galactose oxidase, central domain/Domain of u	—	OG7 LdBPK_220850.1 ↔ LdBPK_365870.1	OG7
LmjF.36.1470 ⚠ kelch motif containing protein, putative	—	OG7 LdBPK_220850.1 ↔ LdBPK_365870.1	OG7
LmjF.28.2150 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_220850.1 ↔ LdBPK_365870.1	OG7
LmjF.32.2150 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070810.1 ↔ LdBPK_365870.1	OG7
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LmjF.25.0410 translation initiation factor SUI1, putative	—	OG6 LdBPK_250420.1 ↔ LdBPK_365870.1 OG7 LdBPK_250420.1 ↔ LdBPK_365870.1	Both
LmjF.12.0280 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1 OG7 LdBPK_120105.1 ↔ LdBPK_365870.1	Both
LmjF.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LmjF.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LmjF.32.3980 Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004705	Both
LmjF.29.0600 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_290620.1 ↔ LdBPK_365870.1 OG7 LdBPK_290620.1 ↔ LdBPK_365870.1	Both
LmjF.30.0730 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_004705	Both
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	Both
LmjF.35.0900 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005125 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005125	Both
LmjF.35.0350 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005080 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005080	Both
LmjF.35.2730 acyl-CoA dehydrogenase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005872	Both
LmjF.19.0800 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006012	Both
LmjF.25.2120 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006404	Both
LmjF.35.0390 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005084 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005084	Both
LmjF.28.2370 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
LmjF.27.0380 Nuclear pore complex protein 158	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007387	Both
LmjF.35.1420 peroxisome targeting signal 1 receptor, putat	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005361 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005361	Both
LmjF.36.0130 PUB domain containing protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_009932 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_009932	Both
LmjF.14.0450 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010327	Both
LmjF.17.0980 Mak10 subunit, NatC N(alpha)-terminal acetylt	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008986 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008986	Both
LmjF.27.1310 arginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005509 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005509	Both
LmjF.25.2410 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010323	Both
LmjF.29.2540 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004998	Both
LmjF.35.4550 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005710	Both
LmjF.18.0880 cyclosporin 16, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006217	OG6
LmjF.33.1120 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004910 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004910	Both
LmjF.36.4040 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008197	Both
LmjF.18.0090 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006141	Both

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