LmjF.18.0880

cyclosporin 16, putative
Leishmania major strain Friedlin OG6: OG6_152675 OG7: OG7_0000556 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.06.0950
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LmjF.18.0090
alpha glucosidase II subunit, putative
— OG6
LmjF.18.0010
kinetoplast polyadenylation/uridylation facto
— OG6
LmjF.30.3300
UV excision repair RAD23-like protein
— OG6
LmjF.30.3440
DNA ligase I, putative
— OG6
LmjF.18.0700
HEAT repeats, putative
— OG6
LmjF.22.0300
hypothetical protein, conserved
— OG6
LmjF.11.0890
hypothetical protein, conserved
— OG6
LmjF.30.0910
ubiquitin-protein ligase, putative
— OG6
LmjF.13.0920
hypothetical protein, conserved
— OG6
LmjF.22.1240
translation initiation factor IF-2, putative
— OG6
LmjF.31.2600
calreticulin, putative
— OG6
LmjF.29.1580
XPC-binding domain containing protein, putati
— OG6
LmjF.19.0800
ABC transport system ATP-binding protein, put
— OG6
LmjF.34.3750
hypothetical protein, conserved
— OG6
LmjF.11.0530
hypothetical protein, conserved
— OG6
LmjF.29.2020
5'-AMP-activated protein kinase catalytic sub
— OG6
LmjF.26.1000
glucosidase II beta subunit-like protein, put
— OG6
LmjF.34.2340
asparaginyl-tRNA synthetase, putative
— OG6
LmjF.35.0350
hypothetical protein, conserved
— OG6
LmjF.18.0600
Zn-finger in Ran binding protein and others/F
— OG6
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG6
LmjF.36.2840
Flagellar Member 2
— OG6
LmjF.32.3980
Gar1/Naf1 RNA binding region, putative
— OG6
LmjF.24.0640
Kinesin-13 3, putative
— OG6
LmjF.28.0450
DIS3-like exonuclease, putative
— OG6
LmjF.36.5620
isoleucyl-tRNA synthetase, putative
— OG6
LmjF.22.1540
alanyl-tRNA synthetase, putative
— OG6
LmjF.25.0170
cleavage and polyadenylation specificity fact
— OG6
LmjF.35.2730
acyl-CoA dehydrogenase, putative
— OG6
LmjF.05.0820
hypothetical protein, conserved
— OG6
LmjF.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmjF.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmjF.29.2110
UDP-glucose:glycoprotein glucosyltransferase,
— OG6
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— OG6
LmjF.29.2540 ⚠
NOL1/NOP2/sun family, putative
— OG6
LmjF.26.1290
Cupin-like domain containing protein, putativ
— OG6
LmjF.35.0390
hypothetical protein, conserved
— OG6
LmjF.30.2320
SET domain containing protein, putative
— OG6
LmjF.17.0350
dihydrouridine synthase (Dus), putative
— OG6
LmjF.36.2420
serine peptidase, Clan SC, Family S9B
— OG6
LmjF.30.1120
importin alpha, putative
— OG6
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG6
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LmjF.20.0250 ⚠
deoxyhypusine synthase, putative
— OG6
LmjF.22.0140
hypothetical protein, conserved
— OG6
LmjF.34.0330 ⚠
deoxyhypusine synthase
— OG6
LmjF.31.2980
hypothetical protein, conserved
— OG6
LmjF.29.0060
tryptophanyl-tRNA synthetase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.