LmjF.34.0330

deoxyhypusine synthase

Leishmania major strain Friedlin OG6: OG6_101093 OG7: OG7_0005231 130 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 130 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.20.0250 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
LmjF.03.0160 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LmjF.30.0910 ⚠ ubiquitin-protein ligase, putative	—	OG6 TCSYLVIO_003155 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003155 ↔ TCSYLVIO_004558	Both
LmjF.11.0890 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001642 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001642 ↔ TCSYLVIO_004558	Both
LmjF.22.0300 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007258	Both
LmjF.30.3440 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	Both
LmjF.30.3300 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
LmjF.18.0010 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
LmjF.06.0340 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LmjF.09.0770 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LmjF.22.1240 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LmjF.22.0590 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
LmjF.26.1290 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
LmjF.29.2110 ⚠ UDP-glucose:glycoprotein glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
LmjF.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LmjF.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LmjF.05.0820 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
LmjF.22.1540 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
LmjF.32.3980 ⚠ Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
LmjF.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LmjF.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LmjF.18.0640 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.21.0150 ⚠ CAMK/CAMKL pseudokinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.36.0900 ⚠ SNF1-related protein kinases, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.07.0900 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.28.2000 ⚠ protein lipid droplet kinase (LDK)	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.22.0810 ⚠ calcium/calmodulin-dependent protein kinase,	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.33.1710 ⚠ CAMK/CAMKL family protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LmjF.34.3430 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
LmjF.33.0310 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LmjF.26.1420 ⚠ FYVE zinc finger, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010724	OG7
LmjF.30.2840 ⚠ GTPase activator-like protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
LmjF.34.1140 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LmjF.15.0980 ⚠ DNA repair protein Rad9, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007065	OG7
LmjF.21.0040 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007258	OG7
LmjF.22.0470 ⚠ Putative tRNA binding domain containing prote	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LmjF.16.1130 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LmjF.36.0470 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LmjF.35.4260 ⚠ predicted zinc finger protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.19.0980 ⚠ FYVE zinc finger, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.26.1260 ⚠ hypothetical protein, unknown function	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.14.1170 ⚠ ras-like small GTPases, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.33.1400 ⚠ STE/STE11 serine/threonine-protein kinase, pu	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007401	OG7
LmjF.35.3500 ⚠ zinc finger protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LmjF.21.0030 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006877 OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007258	OG7
LmjF.30.0700 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010327	OG7

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