LmjF.21.0030

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_200224 OG7: OG7_0033971 202 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 202 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.05.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
LmjF.10.0290 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LmjF.27.0380 ⚠
Nuclear pore complex protein 158
— OG7
LmjF.28.2370 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.14.1320 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LmjF.18.0640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LmjF.21.0640 ⚠
phosphoglucomutase, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— OG7
LmjF.24.0210 ⚠
transcription elongation factor, putative
— OG7
LmjF.34.3750 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LmjF.31.1610 ⚠
diphthine synthase-like protein
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.20.0250 ⚠
deoxyhypusine synthase, putative
— OG7
LmjF.34.0330 ⚠
deoxyhypusine synthase
— OG7
LmjF.13.1100 ⚠
leucyl-tRNA synthetase, putative
— OG7
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LmjF.06.0950 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
LmjF.18.0020 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LmjF.29.2100 ⚠
Present in the outer mitochondrial membrane p
— OG7
LmjF.26.1910 ⚠
deoxyhypusine hydroxylase, putative
— OG7
LmjF.30.3130 ⚠
valyl-tRNA synthetase, putative
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LmjF.13.0730 ⚠
ubiquitin-like protein
— OG7
LmjF.03.0760 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0990 ⚠
UDP-glucose pyrophosphorylase
— OG7
LmjF.16.1340 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.2110 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— OG7
LmjF.31.2810 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LmjF.35.0350 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0080 ⚠
N-myristoyl transferase, putative
— OG7
LmjF.22.1240 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.24.1340 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LmjF.31.1890 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LmjF.31.2020 ⚠
succinyl-diaminopimelate desuccinylase-like p
— OG7
LmjF.33.1610 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LmjF.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmjF.29.1580 ⚠
XPC-binding domain containing protein, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.