LmjF.35.0820

aspartate aminotransferase, putative
Leishmania major strain Friedlin OG6: OG6_100337 OG7: OG7_0003266 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.29.2240 ⚠
Aminopeptidase M1, putative
— Both
LmjF.26.0300 ⚠
aminopeptidase-like protein
— Both
LmjF.12.1250 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LmjF.35.2560 ⚠
cytochrome P450 reductase, putative
— OG7
LmjF.31.2810 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
LmjF.36.0890 ⚠
eukaryotic translation initiation factor 6 (e
— Both
LmjF.36.6250 ⚠
small G-protein, putative
— OG6
LmjF.28.2240 ⚠
hd phosphohydrolase family protein
— Both
LmjF.20.0600 ⚠
hypothetical protein, conserved
— Both
LmjF.18.0990 ⚠
UDP-glucose pyrophosphorylase
— Both
LmjF.14.0350 ⚠
threonine synthase, putative
— Both
LmjF.34.2000 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LmjF.18.0210 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
LmjF.16.0580 ⚠
dihydroorotase, putative
— Both
LmjF.26.2700 ⚠
6-phosphogluconolactonase
— Both
LmjF.21.0040 ⚠
hypothetical protein, conserved
— Both
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG6
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.32.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmjF.31.0570 ⚠
amino acid transporter aATP11, putative
— OG6
LmjF.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.33.0090 ⚠
hypothetical protein, conserved
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— Both
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LmjF.25.1290 ⚠
NPL4 family, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.12.0530 ⚠
glucose-6-phosphate isomerase
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.17.1150 ⚠
5'-3' exoribonuclease B, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmjF.32.2450 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.