LmjF.36.6650

2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Leishmania major strain Friedlin OG6: OG6_103540 OG7: OG7_0008253 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.08.0870
hypothetical protein, unknown function
— OG7
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— Both
LmjF.18.0290 ⚠
dephospho-CoA kinase, putative
— Both
LmjF.28.1110
WD domain, G-beta repeat, putative
— Both
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— Both
LmjF.32.0910
Alpha/beta hydrolase family, putative
— Both
LmjF.28.1140
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.23.1480
alanine racemase, putative
— Both
LmjF.22.0320
SEP domain containing protein, putative
— Both
LmjF.34.3780
phosphomannomutase-like protein
— Both
LmjF.17.0250 ⚠
cystathionine beta-synthase
— Both
LmjF.36.3590 ⚠
cysteine synthase
— OG6
LmjF.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmjF.28.2070
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.01.0220
cyclophilin 12, putative
— OG6
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.24.0770
malic enzyme, putative
— Both
LmjF.28.1970
ribose 5-phosphate isomerase, putative
— Both
LmjF.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.30.1250
pyridoxal kinase, putative
— Both
LmjF.31.2470 ⚠
uridine kinase-like protein
— Both
LmjF.04.0580
spermidine synthase
— Both
LmjF.24.0850
triosephosphate isomerase
— Both
LmjF.14.0350
threonine synthase, putative
— Both
LmjF.26.0830
aspartate--ammonia ligase, putative
— Both
LmjF.34.1040 ⚠
uracil phosphoribosyltransferase, putative
— Both
LmjF.28.2860
cytosolic malate dehydrogenase
— Both
LmjF.29.2800
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LmjF.27.1870 ⚠
trypanothione synthetase
— Both
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmjF.21.0030 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.1740 ⚠
RNA polymerase II, putative
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.36.0900 ⚠
SNF1-related protein kinases, putative
— OG7
LmjF.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.32.3650 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.30.0450 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.