LmjF.28.2860

cytosolic malate dehydrogenase
Leishmania major strain Friedlin OG6: OG6_101066 OG7: OG7_0004490 28 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 28 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.0450
serine carboxypeptidase (CBP1), putative
— Both
LmjF.29.1570 ⚠
glutamamyl carboxypeptidase, putative
— OG7
LmjF.31.1810 ⚠
acetylornithine deacetylase-like protein
— OG7
LmjF.07.0030 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0460 ⚠
trypanothione synthetase, putative
— OG7
LmjF.33.2830 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LmjF.33.2850 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.36.6650
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.07.0270 ⚠
acetylornithine deacetylase-like protein
— Both
LmjF.36.3590 ⚠
cysteine synthase
— OG6
LmjF.17.0250 ⚠
cystathionine beta-synthase
— Both
LmjF.10.1010
nucleoside phosphorylase-like protein
— Both
LmjF.24.2060
transketolase
— Both
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— Both
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.27.1870 ⚠
trypanothione synthetase
— Both
LmjF.29.2800
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LmjF.06.0560
deoxyuridine triphosphatase, putative
— Both
LmjF.26.0830
aspartate--ammonia ligase, putative
— Both
LmjF.14.0350
threonine synthase, putative
— Both
LmjF.04.0580
spermidine synthase
— Both
LmjF.30.1250
pyridoxal kinase, putative
— Both
LmjF.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.27.2030
branched-chain amino acid aminotransferase, p
— Both
LmjF.22.1290 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.