LmjF.27.1870

trypanothione synthetase
Leishmania major strain Friedlin OG6: OG6_111169 OG7: OG7_0010828 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.17.0250 ⚠
cystathionine beta-synthase
— Both
LmjF.36.3590 ⚠
cysteine synthase
— Both
LmjF.26.0830 ⚠
aspartate--ammonia ligase, putative
— Both
LmjF.10.0060 ⚠
thymidylate kinase-like protein
— OG7
LmjF.36.5560 ⚠
aminopeptidase P1, putative
— OG7
LmjF.09.0770 ⚠
oligopeptidase b
— OG7
LmjF.21.1440 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.16.0005 ⚠
anti-silencing protein a-like protein
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.35.2350 ⚠
aminopeptidase P, putative
— Both
LmjF.36.4930 ⚠
translation initiation factor 2 subunit, puta
— Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— Both
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.21.1250 ⚠
adenylate kinase, putative
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.19.0940 ⚠
CAP-Gly domain containing protein, putative
— OG7
LmjF.06.0340 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.11.0350 ⚠
14-3-3 protein 2, putative
— OG7
LmjF.36.3210 ⚠
14-3-3 protein 1, putative
— OG7
LmjF.29.1750 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmjF.01.0530 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.29.1770 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmjF.29.1760 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.25.2110 ⚠
KIF-1 binding protein C terminal, putative
— OG7
LmjF.27.2050 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LmjF.01.0490 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— Both
LmjF.27.2030 ⚠
branched-chain amino acid aminotransferase, p
— Both
LmjF.30.1250 ⚠
pyridoxal kinase, putative
— Both
LmjF.01.0520 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.01.0470 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LmjF.04.0580 ⚠
spermidine synthase
— Both
LmjF.14.0350 ⚠
threonine synthase, putative
— Both
LmjF.06.0560 ⚠
deoxyuridine triphosphatase, putative
— Both
LmjF.29.2800 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
LmjF.28.2860 ⚠
cytosolic malate dehydrogenase
— Both
LmjF.27.1850 ⚠
paraflagellar rod protein 5, putative
— Both
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— Both
LmjF.33.1380 ⚠
mitogen-activated protein kinase 11, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.