LmjF.24.2060

transketolase
Leishmania major strain Friedlin OG6: OG6_100329 OG7: OG7_0003500 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.15.1060 ⚠
tryparedoxin peroxidase
— Both
LmjF.16.0540
aspartate carbamoyltransferase, putative
— Both
LmjF.10.0510
glycerol-3-phosphate dehydrogenase [NAD+], gl
— Both
LmjF.22.0320
SEP domain containing protein, putative
— Both
LmjF.35.0030
pyruvate kinase
— Both
LmjF.30.3520 ⚠
S-adenosylmethionine synthetase
— Both
LmjF.30.3500 ⚠
S-adenosylmethionine synthetase
— Both
LmjF.24.0320 ⚠
fumarate hydratase, putative
— Both
LmjF.29.1960 ⚠
Fumarate hydratase class I, cytosolic
— Both
LmjF.12.0530
glucose-6-phosphate isomerase
— Both
LmjF.15.1160 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1100 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1080 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1040 ⚠
tryparedoxin peroxidase
— Both
LmjF.28.2860
cytosolic malate dehydrogenase
— Both
LmjF.15.1140 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1120 ⚠
tryparedoxin peroxidase
— Both
LmjF.23.0040 ⚠
peroxidoxin
— Both
LmjF.34.4600 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LmjF.20.0970 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.01.0530 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.35.0320 ⚠
serine palmitoyltransferase, putative
— OG7
LmjF.34.3740 ⚠
serine palmitoyltransferase-like protein
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— Both
LmjF.30.2970 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmjF.30.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmjF.03.0230 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LmjF.35.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LmjF.01.0490 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— Both
LmjF.01.0520 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.01.0470 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LmjF.27.0930
isovaleryl-coA dehydrogenase, putative
— Both
LmjF.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmjF.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— Both
LmjF.13.1190
adenylosuccinate synthetase, putative
— Both
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— Both
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— Both
LmjF.32.3260
glucosamine-6-phosphate isomerase, putative
— Both
LmjF.29.0867
guanine deaminase, putative
— Both
LmjF.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LmjF.35.4770
cyclophilin 40
— OG6
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.