LmjF.34.4600

1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase, putative
Leishmania major strain Friedlin OG6: OG6_102069 OG7: OG7_0005923 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.26.0140 ⚠
adenine phosphoribosyltransferase
— Both
LmjF.34.3740 ⚠
serine palmitoyltransferase-like protein
— OG7
LmjF.35.1040 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LmjF.27.0130 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
LmjF.15.0160 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.27.1780 ⚠
casein kinase I-like protein
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.15.0140 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.27.1440 ⚠
Snf7, putative
— OG7
LmjF.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.0320 ⚠
serine palmitoyltransferase, putative
— OG7
LmjF.30.3570 ⚠
Zinc finger CCCH domain-containing protein
— OG7
LmjF.32.2260 ⚠
heat shock protein Hsp20, putative
— OG7
LmjF.32.2630 ⚠
superoxide dismutase, putative
— OG7
LmjF.32.1820 ⚠
iron superoxide dismutase, putative
— OG7
LmjF.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
LmjF.32.1830 ⚠
iron superoxide dismutase, putative
— OG7
LmjF.23.0360 ⚠
NADP-dependent alcohol dehydrogenase, putativ
— OG7
LmjF.25.2130 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LmjF.12.0020 ⚠
PITH domain-containing protein
— OG7
LmjF.35.1480 ⚠
arginase
— OG7
LmjF.12.1130 ⚠
Activating nitroreductase NTR2
— OG7
LmjF.12.1140 ⚠
n-ethylmaleimide reductase-like protein
— OG7
LmjF.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LmjF.32.0080 ⚠
N-myristoyl transferase, putative
— OG7
LmjF.36.6070 ⚠
disgorgin, putative
— Both
LmjF.30.2310 ⚠
hypothetical protein, conserved
— Both
LmjF.36.2140 ⚠
hypothetical protein, conserved
— Both
LmjF.36.4160 ⚠
hypothetical protein, conserved
— Both
LmjF.34.1250 ⚠
PTP1-interacting protein, 39 kDa, putative
— Both
LmjF.36.6160 ⚠
hypothetical protein, conserved
— Both
LmjF.34.0700 ⚠
Uncharacterized conserved protein (DUF2039),
— Both
LmjF.35.1020 ⚠
hypothetical protein, unknown function
— Both
LmjF.26.1010 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2940 ⚠
hypothetical protein, conserved
— Both
LmjF.36.3440 ⚠
Charged multivesicular body protein 3, putati
— Both
LmjF.31.1420 ⚠
hypothetical protein, conserved
— Both
LmjF.24.0500 ⚠
hypothetical protein, conserved
— Both
LmjF.09.0850 ⚠
ras family protein-like protein
— OG6
LmjF.36.3660 ⚠
NUDIX hydrolase 3, putative
— Both
LmjF.35.1010 ⚠
casein kinase, putative
— Both
LmjF.30.2610 ⚠
RNA-binding protein, putative
— OG6
LmjF.32.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmjF.23.1580 ⚠
Nucleoside 2-deoxyribosyltransferase, putativ
— Both
LmjF.10.0810 ⚠
hypothetical protein, conserved
— Both
LmjF.06.0660 ⚠
hypothetical protein, conserved
— Both
LmjF.24.2060 ⚠
transketolase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.