LmjF.25.2130

succinyl-CoA synthetase alpha subunit, putative
Leishmania major strain Friedlin OG6: OG6_100834 OG7: OG7_0005210 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— +2 more Both
LmjF.27.0730 ⚠
reductase, putative
— OG7
LmjF.28.2240 ⚠
hd phosphohydrolase family protein
— Both
LmjF.34.2000 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LmjF.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.34.3780 ⚠
phosphomannomutase-like protein
— Both
LmjF.32.0080 ⚠
N-myristoyl transferase, putative
— Both
LmjF.28.1970 ⚠
ribose 5-phosphate isomerase, putative
— Both
LmjF.06.1070 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.11.0270 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LmjF.15.0240 ⚠
sterol carrier protein, putative
— OG7
LmjF.32.2340 ⚠
cytochrome-b5 reductase, putative
— OG7
LmjF.13.1060 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LmjF.36.3990 ⚠
ATP-dependent protease subunit HslV, putative
— Both
LmjF.35.0320 ⚠
serine palmitoyltransferase, putative
— OG7
LmjF.34.3740 ⚠
serine palmitoyltransferase-like protein
— OG7
LmjF.32.3660 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.32.3670 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.32.3650 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.19.1540 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LmjF.22.0310 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.34.4600 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LmjF.20.0970 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LmjF.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
LmjF.36.4500 ⚠
Protein of unknown function (DUF2870), putati
— Both
LmjF.22.0770 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LmjF.10.0290 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LmjF.31.2470 ⚠
uridine kinase-like protein
— Both
LmjF.23.0690 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LmjF.24.2110 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LmjF.34.1040 ⚠
uracil phosphoribosyltransferase, putative
— Both
LmjF.22.0780 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LmjF.15.0050 ⚠
cytochrome-b5 reductase, putative
— Both
LmjF.26.0140 ⚠
adenine phosphoribosyltransferase
— Both
LmjF.35.0030 ⚠
pyruvate kinase
— Both
LmjF.32.3310 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
LmjF.35.4770 ⚠
cyclophilin 40
— OG6
LmjF.24.0770 ⚠
malic enzyme, putative
— Both
LmjF.32.3680 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— Both
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— Both
LmjF.16.0760 ⚠
transaldolase, putative
— Both
LmjF.21.0845 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.