LmjF.26.0140

adenine phosphoribosyltransferase
Leishmania major strain Friedlin OG6: OG6_101012 OG7: OG7_0003957 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.20.0970 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
LmjF.34.4600 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
LmjF.23.1055
HIT domain containing protein, putative
— Both
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.13.0690 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.26.1710
cytochrome c oxidase subunit V, putative
— Both
LmjF.24.0500
hypothetical protein, conserved
— Both
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.28.1970
ribose 5-phosphate isomerase, putative
— Both
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— Both
LmjF.30.0810
AdoMet dependent proline di-methyltransferase
— Both
LmjF.06.0660
hypothetical protein, conserved
— Both
LmjF.09.1140
hypothetical protein, conserved
— Both
LmjF.26.1820
hypothetical protein, conserved
— Both
LmjF.32.0910
Alpha/beta hydrolase family, putative
— Both
LmjF.30.2610
RNA-binding protein, putative
— OG6
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
LmjF.06.0510 ⚠
U-box domain containing protein, putative
— OG7
LmjF.15.0240 ⚠
sterol carrier protein, putative
— OG7
LmjF.27.1440 ⚠
Snf7, putative
— OG7
LmjF.15.0140 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.27.1780 ⚠
casein kinase I-like protein
— OG7
LmjF.15.0160 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.27.0130 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LmjF.35.1040 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LmjF.30.3570 ⚠
Zinc finger CCCH domain-containing protein
— OG7
LmjF.33.2960 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.30.3470 ⚠
casein kinase 1 isoform 2, putative
— OG7
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.3660
NUDIX hydrolase 3, putative
— Both
LmjF.19.0150
mitogen-activated protein kinase kinase kinas
— OG6
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.32.1830 ⚠
iron superoxide dismutase, putative
— Both
LmjF.08.0290 ⚠
iron superoxide dismutase A, mitochondrial
— Both
LmjF.32.1820 ⚠
iron superoxide dismutase, putative
— Both
LmjF.32.2630 ⚠
superoxide dismutase, putative
— Both
LmjF.01.0450
nicotinamidase, putative
— Both
LmjF.12.0530
glucose-6-phosphate isomerase
— Both
LmjF.34.2410
Aminotransferase class IV, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.