LmjF.34.1040

uracil phosphoribosyltransferase, putative
Leishmania major strain Friedlin OG6: OG6_100147 OG7: OG7_0001754 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0710 ⚠
Protein C21orf2 homolog, putative
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.16.0030 ⚠
arginine N-methyltransferase, type I
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.03.0120 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3310 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LmjF.06.0870 ⚠
protein arginine n-methyltransferase 7
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.25.1700 ⚠
Leucine-rich repeat, putative
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.03.0600 ⚠
arginine N-methyltransferase, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.35.3590 ⚠
DNA repair protein RAD2, putative
— OG6
LmjF.25.2130 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LmjF.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LmjF.11.1160 ⚠
protein transport protein SEC31, putative
— Both
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LmjF.04.0580 ⚠
spermidine synthase
— Both
LmjF.26.0140 ⚠
adenine phosphoribosyltransferase
— Both
LmjF.21.0845 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— Both
LmjF.21.0850 ⚠
xanthine phosphoribosyltransferase
— Both
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LmjF.32.0170 ⚠
U2 small nuclear ribonucleoprotein 40K, putat
— Both
LmjF.06.0540 ⚠
hypothetical protein, conserved
— Both
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— Both
LmjF.29.2360 ⚠
aspartyl aminopeptidase, putative
— Both
LmjF.12.1270 ⚠
arginine N-methyltransferase-like protein
— Both
LmjF.18.0150 ⚠
serine/threonine protein phosphatase type 5,
— OG6
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— Both
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— Both
LmjF.24.0850 ⚠
triosephosphate isomerase
— Both
LmjF.28.1970 ⚠
ribose 5-phosphate isomerase, putative
— Both
LmjF.28.0940 ⚠
oxidoreductase-like protein
— Both
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.