LmjF.36.2140

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_106165 OG7: OG7_0009984 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.06.1180
Nuclear Dbf2-related kinase
— OG6
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.13.0690 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.33.2960 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1820
hypothetical protein, conserved
— Both
LmjF.24.0500
hypothetical protein, conserved
— Both
LmjF.23.1055
HIT domain containing protein, putative
— Both
LmjF.34.0320
hypothetical protein, conserved
— Both
LmjF.25.1290
NPL4 family, putative
— Both
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.28.1700
hypothetical protein, conserved
— Both
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— Both
LmjF.09.0700
hypothetical protein, conserved
— Both
LmjF.11.1010
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
LmjF.36.3220
hypothetical protein, conserved
— Both
LmjF.35.5340
Dynein heavy chain and region D6 of dynein mo
— Both
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.27.1780 ⚠
casein kinase I-like protein
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
LmjF.30.3470 ⚠
casein kinase 1 isoform 2, putative
— OG7
LmjF.17.0260
hypothetical protein, conserved
— OG7
LmjF.04.1090
hypothetical protein, conserved
— OG7
LmjF.27.0590
Domain of unknown function (DUF4470)/Domain o
— Both
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.05.0590 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.30.2820 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.6160
hypothetical protein, conserved
— Both
LmjF.34.4600 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
LmjF.30.2610
RNA-binding protein, putative
— OG6
LmjF.01.0060
hypothetical protein, conserved
— Both
LmjF.30.3170
Tumour suppressor, Mitostatin, putative
— Both
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— Both
LmjF.36.4400 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
LmjF.36.3660
NUDIX hydrolase 3, putative
— Both
LmjF.36.6070 ⚠
disgorgin, putative
— Both
LmjF.01.0450
nicotinamidase, putative
— Both
LmjF.26.1010
hypothetical protein, conserved
— Both
LmjF.09.0850
ras family protein-like protein
— OG6
LmjF.36.2020 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LmjF.32.1850 ⚠
Chaperonin HSP60, mitochondrial
— Both
LmjF.36.2030 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.