LmjF.06.1180

Nuclear Dbf2-related kinase
Leishmania major strain Friedlin OG6: OG6_100850 OG7: OG7_0000103 22 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 22 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.1055
HIT domain containing protein, putative
— OG6
LmjF.25.1290
NPL4 family, putative
— OG6
LmjF.36.4560
PSP1 C-terminal conserved region, putative
— OG6
LmjF.19.0160
metallo-peptidase, Clan MG, Family M24
— OG6
LmjF.09.0540
hypothetical protein, unknown function
— OG6
LmjF.13.0700
kinesin, putative
— OG6
LmjF.36.4400
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmjF.28.1700
hypothetical protein, conserved
— OG6
LmjF.09.0260
G10 protein, putative
— OG6
LmjF.09.0300
hypothetical protein, conserved
— OG6
LmjF.36.0530 ⚠
protein phosphatase 2C-like protein
— OG6
LmjF.06.1070
deoxyribose-phosphate aldolase, putative
— OG6
LmjF.17.0050
hypothetical protein, conserved
— OG6
LmjF.09.0700
hypothetical protein, conserved
— OG6
LmjF.32.1690 ⚠
protein phosphatase 2C, putative
— OG6
LmjF.36.2140
hypothetical protein, conserved
— OG6
LmjF.27.2320 ⚠
protein phosphatase 2C, putative
— OG6
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG6
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG6
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG6
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG6
LmjF.04.0580
spermidine synthase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.