LmjF.36.2030

chaperonin HSP60, mitochondrial precursor
Leishmania major strain Friedlin OG6: OG6_100393 OG7: OG7_0003335 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.34.0130 ⚠
malate dehydrogenase, putative
— OG7
LmjF.28.2820 ⚠
heat shock protein 70, putative
— OG6
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— Both
LmjF.05.0500 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.25.1170 ⚠
ATP synthase subunit beta, mitochondrial, put
— Both
LmjF.24.0940 ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
LmjF.29.2450 ⚠
heat shock protein 20, putative
— Both
LmjF.25.0590 ⚠
hypothetical protein, conserved
— Both
LmjF.30.0260 ⚠
mitochondrial RNA binding protein 1, putative
— Both
LmjF.30.2480 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LmjF.19.0710 ⚠
glycosomal malate dehydrogenase
— OG7
LmjF.35.3900 ⚠
hypothetical protein, conserved
— Both
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.04.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0260 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.11.1010 ⚠
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
LmjF.13.0750 ⚠
hypothetical protein, conserved
— Both
LmjF.33.1810 ⚠
hypothetical protein, conserved
— Both
LmjF.36.2140 ⚠
hypothetical protein, conserved
— Both
LmjF.27.0590 ⚠
Domain of unknown function (DUF4470)/Domain o
— Both
LmjF.34.0320 ⚠
hypothetical protein, conserved
— Both
LmjF.32.0700 ⚠
ubiquitin-conjugating enzyme E2, putative
— Both
LmjF.35.5340 ⚠
Dynein heavy chain and region D6 of dynein mo
— Both
LmjF.36.3220 ⚠
hypothetical protein, conserved
— Both
LmjF.34.0140 ⚠
malate dehydrogenase
— Both
LmjF.34.0160 ⚠
mitochondrial malate dehydrogenase
— Both
LmjF.30.1760 ⚠
microtubule associated protein xmap215
— Both
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.30.2550 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LmjF.30.2490 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LmjF.25.1180 ⚠
ATP synthase subunit beta, mitochondrial, put
— Both
LmjF.07.0220 ⚠
hypothetical protein, conserved
— Both
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— Both
LmjF.09.1130 ⚠
mitochondrial import inner membrane transloca
— Both
LmjF.05.0510 ⚠
ATP synthase F1, alpha subunit, putative
— Both
LmjF.30.2460 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— Both
LmjF.30.2470 ⚠
heat shock 70-related protein 1, mitochondria
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.