LmjF.35.5340

Dynein heavy chain and region D6 of dynein motor/Ankyrin repeats (3 copies), putative
Leishmania major strain Friedlin OG6: OG6_156932 OG7: OG7_0028956 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.1760
microtubule associated protein xmap215
— Both
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.30.2820 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LmjF.17.0260
hypothetical protein, conserved
— OG7
LmjF.04.1090
hypothetical protein, conserved
— OG7
LmjF.34.0320
hypothetical protein, conserved
— Both
LmjF.11.1010
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
LmjF.36.2140
hypothetical protein, conserved
— Both
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LmjF.32.0700
ubiquitin-conjugating enzyme E2, putative
— Both
LmjF.27.0590
Domain of unknown function (DUF4470)/Domain o
— Both
LmjF.33.1810
hypothetical protein, conserved
— Both
LmjF.36.3220
hypothetical protein, conserved
— Both
LmjF.36.2020 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LmjF.32.1850 ⚠
Chaperonin HSP60, mitochondrial
— Both
LmjF.36.2030 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LmjF.13.0750
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.