LmjF.27.0930

isovaleryl-coA dehydrogenase, putative
Leishmania major strain Friedlin OG6: OG6_102105 OG7: OG7_0001034 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0530
glucose-6-phosphate isomerase
— Both
LmjF.01.0470 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LmjF.24.2060
transketolase
— Both
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.15.1120 ⚠
tryparedoxin peroxidase
— Both
LmjF.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LmjF.33.2340 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
LmjF.23.0040 ⚠
peroxidoxin
— Both
LmjF.30.1940 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LmjF.36.1760
aldehyde dehydrogenase, putative
— Both
LmjF.34.0080
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LmjF.35.0030
pyruvate kinase
— Both
LmjF.01.0520 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.15.0980
DNA repair protein Rad9, putative
— OG7
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.30.2970 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.30.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LmjF.01.0530 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.26.0030
pyridoxal phosphate containing glycine decarb
— Both
LmjF.15.1060 ⚠
tryparedoxin peroxidase
— Both
LmjF.03.0230 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LmjF.29.0867
guanine deaminase, putative
— Both
LmjF.35.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LmjF.15.1140 ⚠
tryparedoxin peroxidase
— Both
LmjF.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmjF.13.1190
adenylosuccinate synthetase, putative
— Both
LmjF.15.1160 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1100 ⚠
tryparedoxin peroxidase
— Both
LmjF.01.0490 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LmjF.34.2760
hypothetical protein, conserved
— Both
LmjF.34.3380
aldose 1-epimerase-like protein
— Both
LmjF.30.3520 ⚠
S-adenosylmethionine synthetase
— Both
LmjF.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— Both
LmjF.11.1000
pyruvate phosphate dikinase, putative
— Both
LmjF.32.3260
glucosamine-6-phosphate isomerase, putative
— Both
LmjF.30.1930 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LmjF.15.1080 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1040 ⚠
tryparedoxin peroxidase
— Both
LmjF.06.0370
glutamine synthetase, putative
— Both
LmjF.30.3500 ⚠
S-adenosylmethionine synthetase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.