LmjF.06.0370

glutamine synthetase, putative
Leishmania major strain Friedlin OG6: OG6_100668 OG7: OG7_0003785 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.31.2270
hypothetical protein, conserved
— Both
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— Both
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.27.2330 ⚠
GTP binding protein, putative
— Both
LmjF.21.0140
hypothetical protein, conserved
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.33.2340 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
LmjF.36.4040
hypothetical protein, conserved
— Both
LmjF.19.1010
WD domain, G-beta repeat, putative
— Both
LmjF.08.0890 ⚠
mitochondrial DNA polymerase beta
— Both
LmjF.30.0920
hypothetical protein, conserved
— Both
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— Both
LmjF.34.0080
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LmjF.14.1360
inositol-3-phosphate synthase
— Both
LmjF.11.1000
pyruvate phosphate dikinase, putative
— Both
LmjF.35.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.26.0500 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.05.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0150 ⚠
Leucine-rich repeat, ribonuclease inhibitor s
— OG7
LmjF.33.1540 ⚠
elongation factor 1-gamma, putative
— OG7
LmjF.12.0360 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LmjF.30.1930 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LmjF.08.0900 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
LmjF.27.1830 ⚠
GTP binding protein, putative
— OG7
LmjF.32.3110 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.22.0500
hypothetical protein, conserved
— Both
LmjF.30.1940 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LmjF.09.0740
ubiquitin ligase, putative
— Both
LmjF.35.3230 ⚠
cystathione gamma lyase, putative
— Both
LmjF.34.3380
aldose 1-epimerase-like protein
— Both
LmjF.30.0410
WD-40 repeat protein
— Both
LmjF.30.2980 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmjF.30.2970 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LmjF.15.1010
glutamate dehydrogenase
— Both
LmjF.23.0040 ⚠
peroxidoxin
— Both
LmjF.15.1120 ⚠
tryparedoxin peroxidase
— Both
LmjF.23.0340
(H+)-ATPase G subunit, putative
— Both
LmjF.26.0030
pyridoxal phosphate containing glycine decarb
— Both
LmjF.15.1040 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1080 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1100 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1160 ⚠
tryparedoxin peroxidase
— Both
LmjF.14.0460 ⚠
cystathionine beta-lyase-like protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.