LmjF.30.2980

glyceraldehyde 3-phosphate dehydrogenase, glycosomal
Leishmania major strain Friedlin OG6: OG6_100218 OG7: OG7_0002325 83 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 83 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.1340 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LmjF.27.0930 ⚠
isovaleryl-coA dehydrogenase, putative
— OG7
LmjF.28.2820 ⚠
heat shock protein 70, putative
— OG7
LmjF.23.1460 ⚠
GAF domain/TIP41-like family, putative
— OG7
LmjF.26.0030 ⚠
pyridoxal phosphate containing glycine decarb
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.27.2330 ⚠
GTP binding protein, putative
— OG7
LmjF.27.1830 ⚠
GTP binding protein, putative
— OG7
LmjF.32.3110 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LmjF.27.0030 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
LmjF.30.1800 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
LmjF.11.0130 ⚠
NGG1 interacting factor 3-like protein
— OG7
LmjF.01.0530 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LmjF.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.28.1660 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0530 ⚠
glucose-6-phosphate isomerase
— Both
LmjF.35.0030 ⚠
pyruvate kinase
— Both
LmjF.19.1560 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LmjF.17.0725 ⚠
GMP reductase
— OG6
LmjF.12.0630 ⚠
alanine aminotransferase
— Both
LmjF.28.0825 ⚠
RNA binding protein rbp16, putative
— Both
LmjF.12.1300 ⚠
SET domain containing protein, putative
— OG7
LmjF.29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.15.1450 ⚠
proliferative cell nuclear antigen (PCNA), pu
— OG7
LmjF.27.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.29.1950 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
LmjF.36.5180 ⚠
aldehyde dehydrogenase, putative
— OG7
LmjF.36.1620 ⚠
universal minicircle sequence binding protein
— Both
LmjF.06.1000 ⚠
SET domain containing protein, putative
— OG7
LmjF.33.0510 ⚠
SET domain containing protein, putative
— OG7
LmjF.08.0880 ⚠
SET domain containing protein, putative
— OG7
LmjF.23.0820 ⚠
SET domain containing protein, putative
— OG7
LmjF.27.0160 ⚠
SET domain containing protein, putative
— OG7
LmjF.34.1050 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LmjF.23.0790 ⚠
SET domain containing protein, putative
— OG7
LmjF.24.1750 ⚠
SET domain containing protein, putative
— OG7
LmjF.36.1610 ⚠
universal minicircle sequence binding protein
— OG7
LmjF.18.1580 ⚠
nonspecific nucleoside hydrolase
— Both
LmjF.15.1080 ⚠
tryparedoxin peroxidase
— Both
LmjF.32.3260 ⚠
glucosamine-6-phosphate isomerase, putative
— Both
LmjF.24.0320 ⚠
fumarate hydratase, putative
— Both
LmjF.01.0500 ⚠
fatty acyl CoA synthetase 2, putative
— Both
LmjF.30.3520 ⚠
S-adenosylmethionine synthetase
— Both
LmjF.15.1100 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1160 ⚠
tryparedoxin peroxidase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.