LmjF.01.0220

cyclophilin 12, putative
Leishmania major strain Friedlin OG6: OG6_109053 OG7: OG7_0000556 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmjF.25.1370
TAP42-like family, putative
— OG6
LmjF.08.0480
hypothetical protein, conserved
— OG6
LmjF.14.1190
Bifunctional NAD(P)H-hydrate repair enzyme
— OG6
LmjF.29.1310
carnitine/choline acetyltransferase, putative
— OG6
LmjF.36.0530 ⚠
protein phosphatase 2C-like protein
— OG6
LmjF.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmjF.36.4500
Protein of unknown function (DUF2870), putati
— OG6
LmjF.33.0960
nicotinate phosphoribosyltransferase, putativ
— OG6
LmjF.18.0020
mevalonate-diphosphate decarboxylase, putativ
— OG6
LmjF.36.3580 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LmjF.36.0570
Elongation factor G1, mitochondrial, putative
— OG6
LmjF.26.2370
SPRY domain/HECT-domain (ubiquitin-transferas
— OG6
LmjF.18.0290 ⚠
dephospho-CoA kinase, putative
— OG6
LmjF.10.0290
isocitrate dehydrogenase [NADP], mitochondria
— OG6
LmjF.27.0720
UBA/TS-N domain containing protein, putative
— OG6
LmjF.35.4160 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LmjF.25.2020
hypothetical protein, conserved
— OG6
LmjF.18.0640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG6
LmjF.32.1690 ⚠
protein phosphatase 2C, putative
— OG6
LmjF.20.1690 ⚠
SNAP protein, putative
— OG6
LmjF.21.0640
phosphoglucomutase, putative
— OG6
LmjF.03.0760
hypothetical protein, conserved
— OG6
LmjF.18.0210
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LmjF.25.1290
NPL4 family, putative
— OG6
LmjF.25.2010
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
LmjF.31.1070
biotin/lipoate protein ligase-like protein
— OG6
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG6
LmjF.33.0090
hypothetical protein, conserved
— OG6
LmjF.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.32.0910
Alpha/beta hydrolase family, putative
— OG6
LmjF.36.6650
2,3-bisphosphoglycerate-independent phosphogl
— OG6
LmjF.21.0040
hypothetical protein, conserved
— OG6
LmjF.26.2700
6-phosphogluconolactonase
— OG6
LmjF.16.0580
dihydroorotase, putative
— OG6
LmjF.32.1580
phosphomannose isomerase
— OG6
LmjF.34.2000
pyroglutamyl-peptidase I (C15 family)
— OG6
LmjF.18.0990
UDP-glucose pyrophosphorylase
— OG6
LmjF.20.0600
hypothetical protein, conserved
— OG6
LmjF.36.6250
small G-protein, putative
— OG6
LmjF.36.0890
eukaryotic translation initiation factor 6 (e
— OG6
LmjF.26.1910
deoxyhypusine hydroxylase, putative
— OG6
LmjF.35.4470 ⚠
Co-chaperone protein P23
— OG6
LmjF.35.0030
pyruvate kinase
— OG6
LmjF.12.0020
PITH domain-containing protein
— OG6
LmjF.32.2400
hypothetical protein, conserved
— OG6
LmjF.31.0570
amino acid transporter aATP11, putative
— OG6
LmjF.28.1110
WD domain, G-beta repeat, putative
— OG6
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— OG6
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.